Tramadol 100mg is a centrally acting opioid analgesic prescribed for the relief of moderate to severe pain, both acute (such as post-surgical pain) and chronic (such as osteoarthritis or nerve pain). It acts on the central nervous system by binding to opioid receptors and inhibiting the reuptake of serotonin and norepinephrine, amplifying the body’s response to reduce pain perception.
Tramadol provides significant pain relief, typically beginning within 30–60 minutes. The analgesic effect peaks in about 2–3 hours and typically lasts up to 6 hours for immediate-release forms. Extended-release forms are used for ongoing moderate to severe chronic pain and offer sustained relief, lasting up to 24 hours.
This dose is widely employed for acute injuries, post-operative pain, or chronic conditions where non-opioid pain relievers are insufficient. Prolonged use or overdose can lead to severe risks such as respiratory depression, seizures, serotonin syndrome, and physical dependence. Long-term daily use should only be considered under close medical supervision due to potential development of tolerance, dependence, and other side effects.
Tramadol is available in several forms: oral tablets and capsules (immediate- and extended-release), solutions for injection, and drops. Co-administration with alcohol, benzodiazepines, other opioids, or medications that raise serotonin can greatly increase the risk of dangerous respiratory depression, serotonin syndrome, or overdose. Those with impaired liver or kidney function, seizure disorders, or a history of substance abuse should use tramadol with extreme caution or only with specialist oversight. Non-medical or recreational use is strongly discouraged, given its substantial risk profile for adverse effects, addiction, and potentially life-threatening complications.
• Primary uses: Relief of moderate to severe pain (acute or chronic).
• Onset: Fast acting; pain relief within 30–60 minutes for immediate-release tablets.
• Warnings: Strictly avoid use with alcohol, opioids, or other CNS/serotonergic depressants.
• Risks: Dependence, respiratory depression, seizures, serotonin syndrome, withdrawal if abruptly stopped.
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